Helicid (CAS 80154-34-3) | Pharmaceutical Grade Sedative API | Bulk Helicid Supplier

Helicid, also known as Dushuguoside, is a naturally‑derived active pharmaceutical ingredient (API) for sedation and hypnosis. As a mild central nervous system regulator with non‑addictive and safe pharmacological properties, it serves as a core raw material for pharmaceutical formulations and health products, widely applied in drug manufacturing and R&D to meet high‑standard supply demands in the pharmaceutical industry.

Natural Source & Manufacturing Process

Helicid is categorized as a benzaldehyde‑type aromatic glycoside, distinct from common flavonoids and saponins on the market. It is primarily extracted from the fruits of Helicia nilagirica (commonly called radish tree or dushuguo), a plant in the Proteaceae family, with trace amounts also present in certain legumes, vegetables and fruits.

We adopt mature large‑scale industrial production procedures. Starting from natural plant materials, raw materials undergo strict pretreatment and impurity removal, followed by active ingredient enrichment via organic solvent reflux extraction or water extraction and alcohol precipitation. Further refinement is conducted through column chromatography purification and repeated recrystallization. Strict process parameter control ensures final products comply with pharmaceutical API standards, suitable for direct formulation production and consistent quality assurance for downstream clients.

Pharmacological Profile & Application Scope

As a natural central nervous system regulator, Helicid binds to central neurotransmitter receptors to deliver three core effects: sedation, hypnosis and analgesia. Compared with traditional sedative raw materials, it provides mild yet long‑lasting efficacy without addiction, dependence or severe central inhibition side effects associated with benzodiazepines, delivering superior medication safety.

Clinically, it is widely formulated into products targeting neurasthenia and neurasthenic syndrome, effectively alleviating insomnia, frequent dreaming, dizziness and headaches. It also delivers significant relief for neuropathic pain including primary headache, migraine, trigeminal neuralgia and occipital neuralgia, helping regulate neurological dysfunction and improve patients’ quality of life.

With advances in modern pharmacological research, Helicid has demonstrated broader application potential. It offers strong antioxidant, anti‑inflammatory and neuroprotective benefits by scavenging oxygen free radicals, inhibiting pro‑inflammatory factor release and slowing neuronal aging. Additionally, it exerts positive regulatory and protective effects on the cardiovascular and immune systems, holding promising research value in innovative pharmaceutical fields including anti‑tumor and anti‑apoptosis applications.

Product Safety & Usage Guidelines

Multiple toxicological studies have verified Helicid as a low‑toxic natural pharmaceutical ingredient. Acute and long‑term toxicity tests confirm no significant organ toxicity, mutagenicity or teratogenic risks at therapeutic dosages, with excellent clinical tolerability.

In practical applications, only a small number of users experience mild adverse reactions such as dry mouth, drowsiness and fatigue, which resolve spontaneously upon discontinuation. No severe adverse reactions have been documented. Contraindications and precautions include: prohibition for individuals allergic to Helicid; cautious use for susceptible people, pregnant women and breastfeeding women. High‑purity API must be formulated strictly in accordance with standard pharmaceutical dosages; overdose is forbidden to ensure the safety and compliance of finished pharmaceutical products.

Quality & Logistics Assurance

All Helicid APIs supplied by our company undergo full‑process quality testing via High‑Performance Liquid Chromatography (HPLC), meeting all pharmaceutical API specifications. Purity and physicochemical indicators fully satisfy downstream formulation production requirements. During storage and transportation, direct sunlight and moisture exposure are strictly avoided to preserve crystal form and purity, ensuring stable and consistent batch‑to‑batch quality. We provide reliable natural pharmaceutical raw material supply for pharmaceutical manufacturers and research institutions worldwide.