D-α-Tocopheryl Acid Succinate CAS 4345-03-3 | Stable VE Derivative for Tablets & Capsules Factory Bulk Export

1. Product Overview

Manufacturers of dietary supplements, pharmaceuticals and skincare products often face common production challenges with conventional Vitamin E: easy oxidation and discoloration, moisture absorption and caking, quality attenuation during long ocean shipping, and short finished product shelf life.

D-α-Tocopheryl Acid Succinate is a modified esterified derivative of natural D-alpha tocopherol. Its succinylated structure greatly improves molecular stability, making it highly suitable for automated production of solid dosage forms. Widely adopted in European, American and Japanese nutritional formulas, this stabilized VE material is a premium choice for solid supplement manufacturing.

We supply factory-standard refined D-α-Tocopheryl Acid Succinate with stable batch quality, supporting global sample testing, trial orders and long-term full-container bulk export.

2. Product Specifications

2.1 Basic Parameters

– Product Name: D-α-Tocopheryl Acid Succinate
– Alias: Vitamin E Succinate, VE Acid Succinate
– CAS Number: 4345-03-3
– EINECS Number: 224-403-8
– Molecular Formula: C₃₃H₅₄O₅
– Molecular Weight: 530.78
– Synonyms: α-Tocopherol hemisuccinate, (+)-α-TOCOPHEROL ACID SUCCINATE

3. Core Product Features & Formula Advantages

3.1 Superior Oxidation Stability, Lower Shipment Loss

The phenolic hydroxyl group is blocked by succinic acid groups, providing stronger oxidation resistance than free tocopherol. It resists color fading and content degradation under light, high temperature and long cross-border ocean transportation, effectively extending finished product shelf life and reducing waste during storage and international logistics.

3.2 Ideal for Solid Dosage Production

This modified material features excellent fluidity and anti-caking performance. It avoids moisture agglomeration and layer separation during tableting and capsule filling processes, reducing defective rates and supporting large-scale automated continuous production.

3.3 Wide Formula Compatibility

It can be stably compounded with Vitamin A, powder excipients, plant oils and emulsifying systems. It disperses evenly in nutritional tablets, hard capsules and skincare creams without disrupting existing mature formulas, saving formula adjustment costs for manufacturers.

3.4 Standardized Refining Process & Consistent Batch Quality

Produced through catalytic esterification, low-temperature recrystallization, vacuum desolvation, solvent extraction and water washing purification. Strict quality control on purity, color, impurities and moisture ensures minimal batch difference, meeting long-term stable production requirements for international premium brands.

4. Industrial Application Fields

4.1 Dietary Supplement Raw Material

Used as nutritional fortification ingredient in multivitamin tablets, hard-shell nutritional capsules and solid functional foods, improving the storage stability of finished nutritional products.

4.2 Pharmaceutical Excipient

Serves as a nutritional auxiliary material and intermediate for processing oral solid pharmaceutical formulations.

4.3 Premium Cosmetic Ingredient

Applied in creams and lotions as a lipid stabilizer and liposoluble antioxidant to extend the shelf stability of personal care products.

5. Production & Refining Process

1. Esterification reaction using natural D-alpha tocopherol and succinic anhydride as raw materials, acetone as solvent and triethylamine as catalyst.
2. Low-temperature static cooling to precipitate and remove unreacted succinic anhydride impurities.
3. Vacuum distillation to remove acetone solvent and triethylamine catalyst.
4. N-hexane dissolution, layered filtration and water washing purification to obtain refined D-α-Tocopheryl Acid Succinate.

The standardized industrial process ensures stable recovery rate and consistent high purity for large-scale export orders.

6. Export & Supply Advantages

1. Direct factory supply with stable pricing, sufficient stock and full-container sea shipment support.
2. Complete export documents provided: COA, MSDS and factory qualification files for customs clearance and international vendor audits.
3. Flexible cooperation: sample testing, small trial orders and long-term bulk contract orders are all acceptable; customized packaging available.
4. Professional export-grade sealed & light-proof packaging, specially designed for long-distance ocean shipping to maintain stable physical and chemical indicators.
5. Professional technical support for formula matching, assisting customers in optimizing tablet, capsule and skincare formulations.

7. Storage Conditions

Store in a cool, dry, dark and well-ventilated warehouse. Keep sealed and away from high temperature, humidity and strong oxidizing agents to maintain raw material stability.

8. Inquiry & Cooperation

We specialize in exporting high-purity D-α-Tocopheryl Acid Succinate to global dietary supplement factories, pharmaceutical enterprises and cosmetic manufacturers. Welcome international clients for sample requests, quotations and long-term business cooperation.

Disclaimer

All products on this website are industrial raw materials, food additives, pharmaceutical excipients and cosmetic ingredients for B2B industrial procurement only, not for retail to end consumers. All content is for physical property description, industrial application reference and supply information only, without any medical, health or disease-related claims. All downstream finished products shall comply with local laws, regulations and market access requirements of the importing country. We assume no liability for downstream formula adjustment and final product performance.