D‑Glucuronolactone | CAS 32449‑92‑6 | Liver Protecting API Supplier

D-Glucuronolactone, also known as Glucuronic Acid Lactone, is a classic liver-protective and detoxifying pharmaceutical raw material, as well as a natural endogenous detoxifying active substance in human body. With clear liver-protective and detoxification mechanism, excellent safety and wide global regulatory compliance, it is widely used in global pharmaceutical, dietary supplement and fine chemical industries, and is a well-recognized essential active ingredient in cross-border raw material trade. Our company specializes in supplying pharmacopoeia-grade high-purity D-Glucuronolactone with complete specifications and stable batch quality, which can fully meet the global customers’ procurement and export demands in pharmaceutical API, health care products, pharmaceutical intermediates and other scenarios.

Mechanism of Action

After entering the human body, D-Glucuronolactone is hydrolyzed into glucuronic acid, a core endogenous detoxifying substance in human body with clear and mild mechanism:

– It binds with toxins, drug metabolites, heavy metals and other harmful substances in the liver and intestines to form non-toxic or low-toxic glucuronic acid conjugates

– Greatly improves the water solubility of conjugates, enabling them to be rapidly excreted through the kidneys with urine, effectively reducing the metabolic burden of the liver

– Participates in the repair of liver cell membranes, enhances the metabolism and anti-damage ability of liver cells, improves liver function, and reduces liver damage caused by alcohol, drugs and chemicals

– Has dual functions of liver protection and detoxification, hormone-free, non-dependent, high safety, suitable for long-term auxiliary use

Main Applications

Pharmaceutical API

As a core raw material for liver disease adjuvant therapy and detoxification, it can be made into tablets, capsules, injections and other preparations, used for adjuvant treatment of chronic hepatitis, cirrhosis and abnormal liver function, as well as clinical detoxification intervention for drug poisoning, food poisoning and alcoholic liver injury.

Nutraceuticals & Dietary Supplements

Core raw material for global liver protection, hangover relief, detoxification and staying-up repair dietary supplements, often compounded with silymarin, glutathione, curcumin and other ingredients, suitable for the mainstream health care product markets in Europe, America, Southeast Asia, Middle East, Latin America and other regions.

Fine Chemical & Pharmaceutical Intermediates

Used for the synthesis of fine chemicals such as optically active pyranoglucose and long-chain alkyl furanosides, also as chiral intermediates for the synthesis of some antiviral and anti-infective drugs, and for the preparation of cosmetic active ingredients to assist skin metabolism detoxification and soothing repair.

Our Core Advantages

– Pharmacopoeia-grade Quality Assurance: Two specifications of 95% CP pharmacopoeia grade and 98% high-purity refined grade are available, accurately tested by HPLC, with stable batch quality, and the indicators of heavy metals, microorganisms and pesticide residues meet the global export safety standards

– Global Compliance & Universality: Product standards are in line with international mainstream pharmacopoeias, suitable for the compliance requirements of pharmaceutical and health care products industries in different regions around the world, with no regional restrictions on application scenarios

– Complete Customized Services: Purity, particle size and packaging specifications can be customized according to customer needs, and a full set of export documents such as COA, MSDS, Certificate of Origin and third-party test reports are provided free of charge

– Large-scale Stable Supply: Produced by industrial standardized production, following GMP production standards throughout the process, supporting bulk orders of 50kg-50 tons, with controllable delivery time, meeting the long-term stable procurement needs of global customers

– Safe and Side-effect Free: Natural endogenous active ingredient with clear mechanism, non-dependent, in line with the global safety control requirements of pharmaceutical and health care raw materials

Production Process

Prepared from glucose through oxidation, cyclization, lactonization, refining, recrystallization, drying and screening processes, produced in GMP standard workshop throughout the process, with strict control of solvent residues and impurity content, controllable purity and stable quality, suitable for the global high-end pharmaceutical and health care product raw material market.

Purchase Information

– MOQ: 50kg

– Packaging: 25kg fiber drum, customized packaging available

– Lead Time: 3-7 days for stock orders, 10-15 days for bulk customized orders

– Payment Term: T/T in Advance