L-Proline | 99% USP/EP Grade, Non-Animal Source Bulk Raw Material for Pharma & Food Export

1. Product Overview

L-Proline (CAS 147-85-3) is an essential cyclic natural amino acid. It ranks among the most versatile and widely consumed amino acid raw materials for global pharmaceutical manufacturing, food additives, biological research and agricultural biotechnology.

We supply high-purity L-Proline with stable purity ≥99.0%. Three mainstream export grades are available: Food Grade, USP/EP Pharmacopoeia Grade, and Non-Animal Source Cell Culture Grade.
The product appears as pure white crystalline powder, featuring excellent water solubility, extremely low impurities and stable batch consistency. It complies with international quality standards and meets import requirements of Europe, America, Southeast Asia, the Middle East and other regions. It is a repeatedly ordered raw material for overseas pharmaceutical factories, food manufacturers and biological laboratories.

2. Basic Product Specifications

Spec Parameters

– Name: L-Proline
– English Name: L-Proline
– CAS No.: 147-85-3
– Molecular Formula: C₅H₉NO₂
– Molecular Weight: 115.13
– EINECS No.: 205-702-2
– Appearance: White crystalline powder
– Assay: ≥99.0%
– Solubility: Highly soluble in water, slightly soluble in ethanol, practically insoluble in ether
– Available Grades: Food Grade / USP EP Grade / Non-Animal Source Research Grade

3. Core Advantages for Global Buyers

3.1 Compliant with USP & EP Standards for High-End Pharmaceutical Production

Our pharmacopoeia-grade L-Proline is tested strictly in accordance with USP and EP monographs. Key indicators including heavy metals, loss on drying, residue on ignition and microorganisms are fully controlled.
It serves as a critical synthetic intermediate for Captopril, Enalapril and other mainstream antihypertensive medicines. Consistent low impurity levels help overseas pharmaceutical manufacturers raise finished product qualification rates.

3.2 Non-Animal Source Grade Eliminates Import Traceability Risks

Specially developed for European and American biological research, cell culture and premium health product markets. Our non-animal source L-Proline contains no animal-derived ingredients, removing traceability barriers and satisfying biosafety access standards for overseas laboratories, cell culture medium and bioreagent production.

3.3 Food-Safe & Natural Flavor Enhancer

As an internationally recognized legal food additive and nutritional fortifier, L-Proline triggers the Maillard reaction when heated with saccharides, generating rich and natural aroma. It is widely applied in bakery, meat products, functional food and seasonings, with safe application and no residual odors.

3.4 Great Process Adaptability for Automated Mass Production

Fine, uniform powder with good fluidity and rapid dissolution. No caking or sediment, and will not block automatic feeding equipment. Stable physical and chemical properties extend shelf life and reduce production loss and rework costs for industrial manufacturers.

3.5 Complete Export Documentation for Smooth Global Customs Clearance

Every batch comes with full supporting documents: COA test report, MSDS safety data sheet, microbial & heavy metal analysis, USP/EP test certificates. Certificate of Origin can be provided on request. Standard paperwork supports customs inspection in EU, USA, Southeast Asia and the Middle East.

4. Main Application Fields

4.1 Pharmaceutical Industry

Key raw material for compound amino acid infusion, used for nutritional supplementation after surgery, trauma, gastrointestinal disorders and protein deficiency;
Intermediate for manufacturing antihypertensive pharmaceuticals;
Raw material for biochemical research and cell culture medium.

4.2 Food Industry

Nutritional fortifier, natural flavor enhancer and permitted flavor raw material. Widely used in bakery, beverages, meat products and snack food processing.

4.3 Agricultural Biotechnology

Improve plant salt resistance and stress tolerance, repair cell damage of crops and boost survival rate of callus. Popular raw material for plant tissue culture and biological fertilizer additives.

5. Factory Export Supply Strength

We are a professional manufacturer of L-Proline with large regular stock. Standard 25kg moisture-proof export drum packaging is available.
Flexible order modes: 1kg trial sample orders, small-batch customization and full-container bulk shipments are all acceptable. Neutral export packaging and OEM private labeling services are supported.
Consistent specifications across batches ensure long-term stable raw material supply for global purchasers.

6. Inquiry & Cooperation

If you are seeking a reliable supplier of high-quality L-Proline, please feel free to contact us.
We can provide free samples, latest factory wholesale prices and complete COA documents. Customized raw material solutions can be offered according to your application industry and importing country regulations.

7. Frequently Asked Questions

Q1: Can you supply Non-Animal Source L-Proline?

A: Yes. Non-animal source L-Proline is kept in stock. Free of animal-derived contaminants, it meets standards for cell culture and overseas biological laboratory import. Corresponding supporting statements can be provided.

Q2: Does the product meet USP and EP pharmacopoeia standards?

A: Our pharmacopoeia-grade L-Proline fully complies with USP & EP testing standards. Each batch is attached with complete pharmacopoeia COA, suitable for amino acid infusion and pharmaceutical intermediate production.

Q3: What is your minimum order quantity? Are samples available for testing?

A: 1kg sample orders are supported. Bulk goods are normally supplied in 25kg packages. Flexible terms can be negotiated for long-term major clients.

Q4: What customs clearance documents can you provide for shipment?

A: COA, MSDS, microbial & heavy metal test reports. Certificate of Origin can be arranged upon demand.