Category: Supplement Ingredients
N-Acetylneuraminic Acid Sialic Acid NANA CAS 131-48-6 Food Cosmetic Pharmaceutical Raw Material Factory Supply
– Chinese Name: N-乙酰神经氨酸
– Aliases: Sialic Acid, NANA, N-Acetylneuraminic Acid, Zanamivir Synthetic Intermediate
– English Name: N-Acetylneuraminic Acid
– CAS No.: 131-48-6
– EINECS No.: 205-023-1
– Molecular Formula: C₁₁H₁₉NO₉
– Molecular Weight: 309.27
– Appearance: White to off-white crystalline powder
N-Acetylneuraminic Acid (Sialic Acid NANA) CAS 131-48-6 | Food, Cosmetic & Pharmaceutical Grade Raw Material Factory Bulk Supply

Looking for a reliable bulk supplier of N-Acetylneuraminic Acid, also known as sialic acid NANA? We are a professional manufacturer specializing in synthetic high-purity N-Acetylneuraminic acid with CAS 131-48-6, white crystalline powder in permanent stock, available in food grade, cosmetic grade and pharmaceutical intermediate grade.
Compared with rare and costly sialic acid extracted from bird’s nest, our synthetic NANA features lower cost, consistent batch purity, excellent water solubility and superior storage stability, ideal for mass production by global dietary supplement manufacturers, cosmetic brands and biopharmaceutical enterprises. We provide free test samples, complete English export compliance documents, support all sizes of foreign trade orders, and fully solve overseas buyers’ demands on raw material stocking, customs clearance and formula debugging.
1. Complete Physicochemical Parameters of N-Acetylneuraminic Acid
– Chinese Name: N-乙酰神经氨酸
– Aliases: Sialic Acid, NANA, N-Acetylneuraminic Acid, Zanamivir Synthetic Intermediate
– English Name: N-Acetylneuraminic Acid
– CAS No.: 131-48-6
– EINECS No.: 205-023-1
– Molecular Formula: C₁₁H₁₉NO₉
– Molecular Weight: 309.27
– Appearance: White to off-white crystalline powder
– Solubility: Highly soluble in pure water, clear aqueous solution without mutarotation
– Stability: Maintains full activity for months when sealed and stored at 4℃; aqueous solution resists decomposition
– Available Grades: Food Grade, Cosmetic Grade, Pharmaceutical Intermediate Grade
– Standard Packaging: 1kg aluminum foil vacuum bag (sample size), 25kg fiber drum (bulk shipment)
2. Core Advantages for Bulk Purchasing
1. Industrial Synthetic Process, Perfect Substitute for Bird’s Nest Sialic Acid
Naturally extracted bird’s nest sialic acid suffers limited output, high price and fluctuating purity between batches, which cannot support large-scale brand production. Our self-owned synthetic production line ensures ton-level stable supply. The raw material contains no heavy metals or pesticide residues with controllable purity, greatly cutting long-term raw material procurement costs for overseas manufacturers.
2. Stable Physicochemical Properties, Compatible with Full-Range Industrial Formulations
The crystalline powder resists oxidation and deactivation. It can be added into oral liquids, solid powders, compressed candies, facial serums, moisturizing creams and other finished products, effectively extending shelf life and reducing production waste.
3. Fully Compliant for Global Export Standards
Sialic acid naturally exists in breast milk, bird’s nest and dairy products with high biological safety and zero irritation for cosmetic formulas. Each batch is attached with English COA, MSDS and TDS datasheet, complying with food and cosmetic raw material access standards in Europe, America, Southeast Asia and other regions for smooth customs clearance.
4. Superior Water Solubility & Wide Formula Compatibility
Dissolves in water without turbidity or stratification, suitable for high-end oral drinks and luxury anti-aging skincare lines, without damaging product appearance and texture to upgrade finished product grade.
5. Intact Biological Activity for Consistent Formula Efficacy
Full low-temperature synthetic process locks the native biological activity of sialic acid. Core benefits including immune regulation, skin repair and anti-virus remain unaffected by processing temperature, delivering uniform performance across all batches.
3. Main Application Fields of N-Acetylneuraminic Acid

1. Dietary Supplements & Infant Functional Foods
As a premium nourishing raw material, NANA sialic acid focuses on immune boosting and oral anti-aging effects. Widely applied in children’s nutritional oral liquids, adult anti-aging powders and premium meal replacements, serving as a cost-effective alternative to bird’s nest extract to strengthen product market competitiveness.
2. High-End Skincare Active Ingredient
A globally popular anti-aging repair component added into repair serums, soothing essences and moisturizing creams. It repairs weakened skin barriers, relieves dry and dull skin, with core selling points of anti-inflammation, soothing and anti-aging.
3. Pharmaceutical Intermediate & Biochemical Reagent
Key synthetic substrate for Zanamivir anti-influenza drugs; also applicable to laboratory biochemical testing and biomedical R&D, meeting pharmaceutical industry purity standards.
4. Functional Dairy & Healthy Beverages
Added into premium protein milk and functional drinks to enhance nutritional value, create differentiated high-end health food and build exclusive product selling points.
4. Core Functions of N-Acetylneuraminic Acid Raw Material
Concise science without overstated claims, designed for search traffic acquisition
1. Bidirectionally regulates immune cell response to boost body resistance, a core raw material for immune-support health foods;
2. Blocks the binding pathway between viruses and human cells, delivering natural anti-inflammatory and anti-virus activity for wide pharmaceutical applications;
3. Repairs epidermal skin barriers, alleviates irritation from external environmental damage and delays skin aging, a must-have active ingredient for premium skincare;
4. Neutralizes harmful toxins in the body, protects cells from lysis and optimizes plasma protein metabolism to raise added value of finished products.
5. Factory Foreign Trade Supply Strengths
B-end Buyer Core Keywords: Sialic acid raw material export manufacturer, ton-level NANA in stock
1. Abundant Stock Inventory: Self-owned synthetic production line maintains year-round ton-level inventory, accepting long-term full-container foreign trade orders with stable lead time;
2. Standard Batch Control: Independent English COA test report for every batch, consistent purity, color and solubility to match standardized mass production of brands;
3. Complete Export Documents: One-stop supply of MSDS, TDS specification sheets and customs declaration documents, meeting audit standards of customs worldwide;
4. Free Sample Support: Free delivery of 10g/100g samples; sample logistics fee can be deducted upon bulk order confirmation;
5. Custom Value-Added Services: Custom packaging, purity grading and formula technical guidance available to satisfy differentiated production demands of clients.

6. Frequently Asked Questions (FAQ)
Q1: Is there any functional difference between synthetic N-Acetylneuraminic Acid and natural bird’s nest sialic acid?
A: They share identical molecular structure and biological activity. Synthetic NANA features higher purity, fewer impurities, stable supply and lower procurement cost. At present, most overseas health food and cosmetic brands adopt synthetic sialic acid as raw material.
Q2: Is N-Acetylneuraminic Acid hard to store? Will finished products lose efficacy easily?
A: This crystalline powder owns extremely strong stability. It retains full activity for months under sealed low-temperature storage, and its aqueous solution resists decomposition far better than common plant-extracted active raw materials.
Q3: Can NANA sialic acid be exported to Europe, America, Southeast Asia and other overseas markets?
A: Food, cosmetic and pharmaceutical grades are all available for global export. Complete English compliance documents are provided to meet raw material audit standards of customs in all countries.
Q4: Do you support small trial orders and long-term annual framework cooperation?
A: We support 1kg trial samples, 25kg small batches and ton-level full-container bulk orders. Long-term supply framework agreements can be signed to lock stable factory prices.
7. Request Quotation & Samples
If you are a health food manufacturer, cosmetic brand owner or biomedical R&D enterprise looking for bulk purchase of N-Acetylneuraminic Acid (Sialic Acid NANA CAS 131-48-6), feel free to contact us online.
Upon inquiry, you can obtain free resources: English COA test report, TDS technical datasheet, factory foreign trade ex-factory quotation, formula test samples and long-term stable supply cooperation plan.
Kindly inform us your application industry and monthly purchase volume, and we will provide a complete foreign trade cooperation proposal within 24 hours.
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