Category: Supplement Ingredients
Calcium Alpha-Ketoglutarate Ca-AKG CAS 402726-78-7 | 99% Export Grade Supplier
Chinese Name: α-酮戊二酸钙
English Name: Calcium Alpha-Ketoglutarate (Ca-AKG)
Alias: Calcium 2-oxo-1,5-pentanedioate
CAS No.: 402726-78-7
Purity: ≥99%
Appearance: Fine, uniform white powder
Grade: Export Grade for Dietary Supplements
Physical Properties: Good flowability, stable water solubility, strong thermal tolerance during processing
Storage: Store in a sealed, cool, dry and dark environment
Shelf Life: 24 months
Calcium Alpha-Ketoglutarate (Ca-AKG)

1. Product Introduction
Calcium Alpha-Ketoglutarate (Ca-AKG) is a natural core intermediate of the human tricarboxylic acid (TCA) cycle. It has become one of the fast-growing popular raw materials for dietary supplements across Europe, America, Australia and Southeast Asia.
Our 99% high-purity Ca-AKG is produced under standardized quality control, featuring excellent batch consistency with minimal fluctuation in color and content. It delivers reliable solubility and processing stability, suitable for capsules, tablets, powder blends, oral liquids and most mainstream dosage forms. We are a stable supplier for overseas brands and import distributors.
2. Solutions to Common Sourcing Pain Points
Many buyers frequently encounter difficulties when sourcing Ca-AKG from other suppliers, which we fully address with optimized quality control and export service packages:
❌ Unstable batch specifications and uneven powder color, hindering standardized mass production
❌ Poor water solubility, leading to complicated formulation development and limited dosage options
❌ Incomplete documentation without English COA or MSDS, causing customs clearance delays
❌ High minimum order quantities, making it impossible to run small-scale formulation trials first
We provide consistent quality, complete standard export documents and flexible sampling policies to meet full-chain import requirements.
3. Core Commercial & Formulation Advantages
3.1 Supported by Published Research for Differentiated Positioning
Ponce De Leon Health has published long-term animal trial research, which observed positive impacts on the general health status of test subjects with Ca-AKG supplementation.
These publicly available research findings serve as solid references for differentiated mid-to-high-end supplement formulations, creating clear market advantages over basic generic nutrients.
3.2 Multi-industry Versatility to Simplify Your Purchasing List
This single ingredient fits a wide range of high-demand wellness categories globally, helping you streamline procurement and inventory management:
1. General healthy aging support supplements
2. Sports nutrition and physical performance formulas
3. Bone & skin care complex nutrients
4. Senior comprehensive nutritional supplements
5. Daily immune support functional foods
3.3 Endogenous Human Metabolite with Wide Global Recognition
As a naturally occurring metabolite inside the human body, Ca-AKG features gentle properties and good biocompatibility. It has a long application history worldwide with mature registration procedures in most regions, bringing lower commercial risks for long-term stable distribution.
3.4 Metabolic Functions for Versatile Formulation Design
1. Participates in the body’s energy metabolism pathways, widely adopted in physical endurance formulations
2. Takes part in amino acid conversion, ideal for protein and collagen-supporting blends
3. Exhibits antioxidant properties, commonly used in antioxidant complex supplements
4. Supports metabolic activities of immune cells for immune care formulas
5. Contributes to cerebral metabolism, applicable for cognitive nutrition supplements
Disclaimer: This product is solely a food-grade raw material, not a pharmaceutical ingredient. End-product marketing claims must strictly comply with local advertising regulations in your target market. No claims for disease treatment or prevention are permitted.

4. Complete Product Specifications
Chinese Name: α-酮戊二酸钙
English Name: Calcium Alpha-Ketoglutarate (Ca-AKG)
Alias: Calcium 2-oxo-1,5-pentanedioate
CAS No.: 402726-78-7
Purity: ≥99%
Appearance: Fine, uniform white powder
Grade: Export Grade for Dietary Supplements
Physical Properties: Good flowability, stable water solubility, strong thermal tolerance during processing
Storage: Store in a sealed, cool, dry and dark environment
Shelf Life: 24 months
5. Exclusive Export Supply Advantages
✅ Permanent in-stock inventory and large-scale stable production capacity, annual supply contracts available
✅ Batch-specific COA certificates, complete English MSDS and customs documents to meet international clearance standards
✅ Flexible MOQ, small trial samples available to reduce your upfront formulation R&D costs
✅ Custom neutral export packaging and private labeling services on request
✅ Free technical consultation for formulation blending and production optimization

6. Call to Action
Driven by rising global demand for wellness ingredients, Ca-AKG remains a high-growth nutritional raw material in recent years.
Feel free to contact us to request samples, full test certificates or a customized quotation.
Product Inquire Now
"*" indicates required fields
