L-5-Methyltetrahydrofolate Calcium CAS151533-22-1 | Directly Absorbable Active Folic Acid for Premium Supplements

Stop Low-Margin Folic Acid Competition — Higher Absorption, Higher Product Premium

Conventional synthetic folic acid requires complex enzymatic metabolism in the human body.
It shows poor absorption for pregnant women, the elderly, and people with weak metabolism, resulting in weak finished product efficacy, low repurchase rate, and serious homogeneous price competition.

L-5-Methyltetrahydrofolate Calcium (5-MTHF-Ca) is the final natural active form of folate in the human body.

✅ No metabolism required, directly bioavailable
✅ Far higher bioactivity than ordinary folic acid
✅ Top preferred raw material for EU & US premium prenatal and cardiovascular supplements
✅ Perfect formula differentiation to increase your terminal profit margin

1. Product Specifications & Basic Information

Basic Data

– Product Name: L-5-Methyltetrahydrofolate Calcium
– Alias: 5-MTHF-Ca, Levomefolate Calcium, Active Folic Acid
– CAS No.: 151533-22-1
– Molecular Formula: C₂₀H₂₃CaN₇O₆
– Molecular Weight: 497.53
– CBNumber: CB11420680

Physical Properties

– Appearance: Off-white to light yellow fine powder
– Stability: Uniform powder, no caking, high crystal stability
– Solubility: Excellent water solubility
– Application Forms: Capsules, tablets, powder blends, oral liquids, functional nutritional formulas

2. Core Competitive Advantages for Buyers

1. Direct Utilization Without Metabolic Conversion

L-5-Methyltetrahydrofolate Calcium is the only naturally existing and usable folate form in human plasma and cells.

Unlike ordinary folic acid, it skips enzymatic conversion and directly participates in:

– DNA synthesis & cell repair
– Human methylation metabolism
– Nervous system nutritional support

It guarantees stable and visible efficacy for finished products.

2. Fit Four High-Profit Global Market Tracks

Ideal for high-end, high-repurchase functional product lines:

1. Prenatal & postnatal maternal nutrition supplements
2. Cardiovascular health formulas for lowering homocysteine
3. Gentle growth nutrition for children
4. Metabolic disorder crowd nutritional products

3. Rich Finished Product Selling Points

– Effectively reduce homocysteine levels and protect vascular health
– Support cell proliferation and DNA damage repair
– Maintain healthy nervous system function
– Reduce the risk of fetal neural tube defects during pregnancy

3. Global Main Applications

Premium Prenatal Supplement Raw Material

Widely adopted by high-end maternal nutrition brands in Europe, America and Southeast Asia. It replaces traditional synthetic folic acid and becomes the core differentiated ingredient.

Cardiovascular Health Formula

Stable global demand for middle-aged and elderly vascular care and homocysteine regulation products.

All-Age High-End Nutritional Products

Mild, non-metabolic burden, suitable for full-age high-quality nutritional supplements with better customer reputation.

Pharmaceutical & Research Raw Material

Meets high-purity standards for pharmaceutical preparations, biochemical experiments and methylation mechanism research.

4. Factory Export Advantages

✅ Long-term stable factory stock with consistent batch quality
✅ Fine uniform powder, suitable for mass production formulas
✅ Complete export documents: COA, MSDS, Test Reports for global customs clearance
✅ Free sample support, small trial orders & bulk container orders acceptable
✅ Compliant with European, American and Southeast Asian food-grade standards

5. Inquiry & Sample Service

Contact us for the latest batch price, free samples, full technical documents and compliance files.