Bisbentiamine (CAS 2667‑89‑2) | Alkali‑Resistant & Anti‑Thiaminase Low‑Loss Vitamin B1 Derivative

Many food processing plants, bakeries and feed manufacturers are troubled by a common production issue. Conventional thiamine hydrochloride (Vitamin B1) loses activity easily under alkaline conditions. It can be destroyed by thiaminase and is hygroscopic. Heavy nutrient loss occurs during processing, water‑washing sterilization and long‑term storage. Even with sufficient dosing, finished products may fail specification tests, resulting in material waste and scrapped batches, which raises overall production costs.

Bisbentiamine (CAS 2667‑89‑2) is a modified upgraded vitamin B1 derivative designed to solve the drawbacks of standard thiamine. Featuring alkali resistance, anti‑thiaminase performance, non‑hygroscopic property and minimum processing‑storage loss, it has become a popular differentiated raw material for overseas grain fortification, bakery and feed industries.

Why Overseas Manufacturers Choose Bisbentiamine

1. Excellent Alkali Resistance to Cut Processing & Storage Loss

Ordinary thiamine salts rapidly deactivate in weak‑alkaline environments. Bisbentiamine delivers outstanding alkali tolerance and is non‑hygroscopic with no caking risk.
It adapts to high‑temperature weak‑alkaline production conditions such as baking and noodle manufacturing. Active ingredients remain well‑preserved throughout shelf life, helping buyers reduce material waste and control production costs.

2. Resist Thiaminase to Preserve Full Vitamin B1 Activity

Conventional vitamin B1 is readily degraded by thiaminase and loses its function.
Bisbentiamine is not decomposed by thiaminase. It is especially suitable for grain‑fortified formulas. Vitamin B1 activity remains intact even after water‑washing procedures, making it a classic raw material for industrial enriched‑rice production.

3. Multi‑Sector Application with Stable Overseas Procurement Demand

Beyond food nutrition fortification, it is widely adopted in health supplements, animal feed and laboratory research. Food factories, nutrition brands, feed producers and research institutes keep steady purchasing demand, suitable for long‑term bulk stock‑up.

Export‑Grade Product Specifications

Product Name: Bisbentiamine
CAS No.: 2667‑89‑2
Molecular Formula: C₃₈H₄₂N₈O₆S₂
Molecular Weight: 770.92
Appearance: White to off‑white crystalline powder, odorless, slightly bitter taste
Melting Point: 141‑147℃
Solubility: Soluble in chloroform; slightly soluble in methanol and ethanol; practically insoluble in water and ether; soluble in aqueous solutions of inorganic salts and organic acids
Available Grade: Food Fortification Grade / Feed Grade / Research Reagent Grade
Key Properties: Alkali‑resistant, non‑hygroscopic, anti‑thiaminase, excellent storage stability

Product Function & Process Characteristics

Bisbentiamine is a synthetic modified vitamin B1 derivative retaining complete vitamin B1 physiological activity.
Modified molecular structure enables stable performance under weak‑alkaline conditions. Its stability in acidic to weakly‑acidic aqueous solution is comparable to thiamine hydrochloride.

Typical industrial application for enriched rice: Dissolve Bisbentiamine in dilute acetic acid to soak rice, then treat with ammonia vapor followed by air‑drying. This greatly reduces vitamin B1 loss caused by water washing and realizes efficient grain nutrition fortification.

Main Overseas Application Scenarios

– Food Industry: Vitamin B1 fortification for rice, wheat flour, bread, instant noodles, pastries, dairy products, soy sauce and more
– Nutraceutical Field: Dietary supplements, health‑care products and pharmaceutical raw materials
– Animal Nutrition: Aquafeed, pet food, livestock vitamin premixes
– Scientific Research: Biological and pharmacological research reagents

Our Global Export Advantages

As a reliable exporter of Bisbentiamine, we meet international B‑side procurement standards:
✅ Uniform crystalline powder with stable batch‑to‑batch quality and controlled purity
✅ Flexible orders: lab samples, small trial lots and large‑volume bulk shipments are all available
✅ Complete export documentation for smooth customs clearance worldwide
✅ Neutral export packaging with customizable specifications
✅ In‑stock inventory to support continuous production for clients

If you are sourcing a high‑stability vitamin B1 derivative, please contact us for COA, latest quotation and free sample support.