Palmatine 101: Ultimate Guide to Its Applications, Sources & Solubility for Global Buyers
In the global natural active ingredients and botanical extract market, palmatine (also known as palmatine, fibrauretine, CAS No. 3486-67-7; hydrochloride: 10605-02-4) stands out as a star isoquinoline alkaloid with huge commercial potential and broad industrial value.
Derived from premium traditional Chinese medicinal herbs, this high-purity natural alkaloid has gained massive traction among pharmaceutical manufacturers, daily chemical brands, feed factories and R&D institutions worldwide—thanks to its powerful broad-spectrum bioactivity, wide safety margin and diverse application scenarios.
This in-depth FAQ guide breaks down everything you need to know about palmatine, from its cutting-edge industrial applications, sustainable natural sources to precise laboratory solubility data, helping you seize global market opportunities and source high-quality bulk palmatine raw materials with confidence.
Q1: What Are the Core Applications & Market Advantages of Palmatine?
Unlike ordinary natural botanical ingredients, palmatine delivers multi-scenario, high-value applications backed by modern pharmacological research, making it a top sought-after raw material across global pharmaceutical, daily chemical and feed industries:
Pharmaceutical & Clinical Use (Highest Commercial Value)
As the key active component of fibrauretine preparations, high-purity palmatine features broad-spectrum antibacterial, anti-inflammatory and antiviral properties. It is widely formulated into tablets, capsules, suppositories and injections for treating:
– Gynecological infections (candidal vaginitis, pelvic inflammatory disease)
– Gastrointestinal disorders (enteritis, bacillary dysentery, Helicobacter pylori-associated gastritis)
– Respiratory and urinary tract infections, skin soft tissue infections
It effectively inhibits drug-resistant Staphylococcus aureus, fungi and multiple viruses, serving as a safe natural alternative to traditional antibiotics—highly aligned with global demand for antibiotic reduction, green clinical treatments and natural pharmaceutical ingredients.
Cutting-Edge Pharmacological R&D
Modern scientific studies have unlocked its far-reaching therapeutic potential, making it a hot target for innovative drug development and academic research:
– Anti-tumor: Inhibits proliferation and metastasis of breast, colon, prostate and liver cancer cells
– Neuroprotection: Improves neuronal repair, with great potential for neurodegenerative disease research
– Metabolic regulation: Anti-atherosclerosis, hypoglycemic, lipid-lowering and liver-kidney protective effects
– Immune & intestinal health: Regulates intestinal flora, repairs intestinal barrier, and acts as a potent IDO-1 inhibitor
Daily Chemical & Feed Industries
– Daily chemicals: Natural antibacterial agent for intimate care lotions, skincare products and antibacterial detergents
– Feed additives: Improves animal intestinal health, enhances disease resistance, reduces antibiotic use, and boosts breeding efficiency
Q2: Where Does Palmatine Come From? Our Sustainable, High-Quality Sources
Palmatine is a naturally occurring isoquinoline quaternary ammonium alkaloid, extracted from pure, non-polluting botanical raw materials with strict sustainable sourcing and quality control:
1. Primary industrial source: Stem of Fibraurea recisa Pierre (Menispermaceae), the core raw material for high-purity bulk palmatine production
2. Complementary herbal sources: Bark of Phellodendron chinense & Phellodendron amurense (Rutaceae), rhizome of Coptis chinensis (Ranunculaceae), and Mahonia fortunei (Berberidaceae)
We adhere to green extraction process and international quality standards: all raw materials are 100% traceable, free of heavy metals, pesticide residues and harmful microbes, fully meeting EU, US and global pharmaceutical grade, food grade quality requirements.
Q3: What Is the Exact Solubility of Palmatine? Critical for R&D & Formulation
Palmatine exists in two stable commercial forms, with distinct solubility profiles for different laboratory R&D and industrial production needs:
Free Palmatine (CAS: 3486-67-7)
– Soluble in hot water, slightly soluble in cold water
– Sparingly soluble in ethanol, chloroform; practically insoluble in diethyl ether
– Freely soluble in DMSO, methanol and dilute acid solutions
Palmatine Hydrochloride (CAS: 10605-02-4, Pharmaceutical Grade)
– Moderately soluble in water, solubility increases significantly in hot water
– Soluble in DMSO, methanol; slightly soluble in chloroform, ethanol
– Practical laboratory reference: Solubility in DMSO ≈ 64 mg/mL, ideal for drug formulation, scientific research and industrial production
Our professional technical team provides targeted solubility guidance and customized formulation support, helping you optimize product R&D efficiency and reduce production costs.
Why Choose Us as Your Trusted Palmatine Supplier?
✅ Customizable High-Purity Specifications: 98%, 99% pharmaceutical grade/food grade palmatine, support bulk customization
✅ Strict Full-Cycle Quality Control: Complete COA, MSDS, certification documents, stable batch consistency
✅ Reliable Global Supply: Large-scale production capacity, fast global delivery, professional logistics & customs clearance
✅ Tailored Technical Solutions: Exclusive application support for pharmaceutical, daily chemical and feed industries
✅ Competitive Bulk Pricing: Cost-effective quotes for long-term cooperative partners
If you are looking for a reliable bulk palmatine supplier, high-purity palmatine extract manufacturer with stable quality and professional service, contact us today for a free sample and exclusive quotation! Let’s explore the unlimited business potential of this premium natural active alkaloid together.
Palmatine / Fibrauretine – High Purity Natural Medicinal Plant Extract Manufacturer